Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4821013 | 0.97 | ALOX12 (0.33) | LMNAMEN1CYP3A4CYP2C9NFKB1 | |
| SCHEMBL2147484 | 0.94 | KMT2A (0.31) | LMNAMEN1CYP3A4CYP2C9NFKB1 | |
| SCHEMBL915632 | 0.84 | KMT2A (0.33) | LMNAMEN1CYP3A4CYP2C9NFKB1 | |
| SCHEMBL9910887 | 0.84 | SMN1; SMN2 (0.38) | LMNACYP2C9KMT2A | |
| SCHEMBL1949595 | 0.83 | ALOX12 (0.38) | CYP3A4 | |
| SCHEMBL13748507 | 0.83 | ALOX12 (0.38) | CYP3A4 | |
| SCHEMBL13606692 | 0.82 | ALOX12 (0.32) | — | |
| SCHEMBL13541624 | 0.82 | ALDH1A1 (0.42) | LMNAMEN1CYP3A4CYP2C9KMT2A | |
| SCHEMBL1280224 | 0.82 | ALOX12 (0.37) | CYP3A4 | |
| SCHEMBL2193456 | 0.81 | MEN1 (0.35) | LMNAMEN1CYP3A4CYP2C9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | disclosed |