Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699686 | 0.88 | TDP1 (0.35) | MEN1LMNACYP3A4CYP2C9NFKB1 | |
| SCHEMBL4698289 | 0.85 | ALDH1A1 (0.35) | MEN1LMNACYP3A4CYP2C9NFKB1 | |
| SCHEMBL915632 | 0.84 | KMT2A (0.33) | MEN1LMNACYP3A4CYP2C9NFKB1 | |
| SCHEMBL2147484 | 0.84 | KMT2A (0.31) | MEN1LMNACYP3A4CYP2C9NFKB1 | |
| SCHEMBL917125 | 0.84 | MEN1 (0.36) | MEN1LMNACYP3A4CYP2C9NFKB1 | |
| SCHEMBL4698309 | 0.84 | PRKCA (0.36) | MEN1LMNACYP3A4CYP2C9NFKB1 | |
| SCHEMBL1764576 | 0.83 | KMT2A (0.49) | MEN1LMNACYP3A4CYP2C9NFKB1 | |
| SCHEMBL12972246 | 0.83 | KMT2A (0.35) | MEN1LMNACYP3A4CYP2C9NFKB1 | |
| SCHEMBL4698290 | 0.82 | MAPT (0.35) | MEN1LMNACYP3A4CYP2C9NFKB1 | |
| SCHEMBL1346331 | 0.82 | MEN1 (0.31) | MEN1LMNACYP3A4CYP2C9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091164-A1 | ORAL DOSAGE FORMS HAVING A HIGH LOADING OF A TRANEXAMIC ACID PRODRUG | XENOPORT, INC. (US) | 2011-07-28 | — | — | WO | disclosed |
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2008013860-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF ALPHA-AMINO ACIDS, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2008-01-31 | — | — | WO | disclosed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | disclosed |