Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.37 |
| ▸ | USP5 | P45974 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698677 | 0.95 | SLC18A3 (0.39) | SLC18A3USP5CHRM4USP30MMP3 | |
| SCHEMBL4698135 | 0.86 | USP5 (0.44) | USP5USP30MMP3KCNH2GRIN2B | |
| SCHEMBL4702692 | 0.80 | MMP2 (0.46) | MMP3MCL1 | |
| SCHEMBL4698467 | 0.75 | F10 (0.42) | MMP3MCL1 | |
| SCHEMBL4700809 | 0.73 | MMP2 (0.45) | USP30MMP3MCL1 | |
| SCHEMBL14040629 | 0.71 | USP5 (0.46) | USP5USP30MMP3KCNH2GRIN2B | |
| SCHEMBL14040636 | 0.71 | MMP13 (0.40) | — | |
| SCHEMBL14040502 | 0.71 | MMP13 (0.40) | — | |
| SCHEMBL4699851 | 0.70 | MMP13 (0.42) | USP30MMP3 | |
| SCHEMBL5882183 | 0.68 | F10 (0.44) | USP30MMP3MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444202-B1 | NOVEL METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-10-15 | — | — | EP | disclosed |