Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.56 |
| ▸ | ABAT | P80404 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27581272 | 0.91 | GPR35 (0.53) | GPR35MAPK1TP53HPGDTSHR | |
| SCHEMBL648045 | 0.83 | GPR35 (0.62) | GPR35MAPK1TP53HPGDTSHR | |
| SCHEMBL19113276 | 0.81 | ERN1 (0.45) | GPR35MAPK1TP53HPGDTSHR | |
| SCHEMBL6840900 | 0.80 | TSHR (0.56) | GPR35MAPK1TP53HPGDTSHR | |
| SCHEMBL1665978 | 0.78 | PARP1 (0.56) | GPR35MAPK1TP53HPGDTSHR | |
| SCHEMBL14371934 | 0.78 | MAPT (0.43) | GPR35MAPK1TP53TSHRALDH1A1 | |
| SCHEMBL4368126 | 0.78 | MAPT (0.67) | GPR35MAPK1TP53HPGDTSHR | |
| SCHEMBL69947 | 0.78 | MAPK1 (0.67) | GPR35MAPK1TP53HPGDTSHR | |
| SCHEMBL6031674 | 0.78 | MAPK1 (0.67) | GPR35MAPK1TP53HPGDTSHR | |
| SCHEMBL29502912 | 0.78 | MAPK1 (0.67) | GPR35MAPK1TP53HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114113370-B | Analysis method of aromatic halogenated disinfection byproducts in water | 东南大学 | 2024-03-26 | — | — | CN | claimed |
| CN-114113370-A | Analysis method of aromatic halogenated disinfection byproducts in water | 东南大学 | 2022-03-01 | — | — | CN | claimed |
| EP-0460111-B1 | PREPARATION OF 4-SUBSTITUTED ARYL OLEFINS | EASTMAN KODAK CO (US) | 1993-12-08 | — | — | EP | claimed |
| EP-0460111-A1 | PREPARATION OF 4-SUBSTITUTED ARYL OLEFINS. | EASTMAN KODAK CO (US) | 1991-12-11 | — | — | EP | claimed |
| US-4965361-A | CATALYTIC REACTION OF 4-SUBSTITUTED ARYL IODIDE WITH OLEFIN IN ESTER SOLVENT | EASTMAN KODAK COMPANY (US) | 1990-10-23 | — | — | US | claimed |
| EP-0388322-A1 | Preparation of 4-substituted aryl olefins | EASTMAN KODAK COMPANY (US) | 1990-09-19 | — | — | EP | claimed |
| WO-1990009973-A1 | PREPARATION OF 4-SUBSTITUTED ARYL OLEFINS | EASTMAN KODAK COMPANY (US) | 1990-09-07 | — | — | WO | claimed |
| US-20250171427-A1 | THERAPEUTIC COMPOUNDS | SANOFI (FR) | 2025-05-29 | — | — | US | disclosed |
| WO-2025104230-A1 | BENZOXAZOLES AS MODULATORS OF IL-17A | SANOFI (FR) | 2025-05-22 | — | — | WO | disclosed |
| US-20250154107-A1 | 3,4-Dihydroisoquinolin-1(2H)-Ones Derivatives as STING Antagonists and the Use Thereof | BEIGENE SWITZERLAND GMBH (CH) | 2025-05-15 | — | — | US | disclosed |
| EP-4448513-A1 | 3, 4-DIHYDROISOQUINOLIN-1 (2H) -ONES DERIVATIVES AS STING ANTAGONISTS AND THE USE THEREOF | BeiGene Switzerland GmbH (CH) | 2024-10-23 | — | — | EP | disclosed |
| US-20240254138-A1 | TRICYCLIC PYRIMIDINES AS CYCLIN-DEPENDENT KINASE 7 (CDK7) INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-08-01 | — | — | US | disclosed |
| CN-118401514-A | 3, 4-Dihydroisoquinolin-1 (2H) -one derivatives as STING antagonists and uses thereof | 百济神州有限公司 | 2024-07-26 | — | — | CN | disclosed |
| EP-0522469-A2 | Preparation of poly(benz(ox, imid, thi)azole) polymers | EASTMAN KODAK COMPANY (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5149755-A | Aroatmic amine and halide reactants | EASTMAN KODAK COMPANY (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0460111-A1 | PREPARATION OF 4-SUBSTITUTED ARYL OLEFINS. | EASTMAN KODAK CO (US) | 1991-12-11 | — | — | EP | disclosed |
| US-4965361-A | CATALYTIC REACTION OF 4-SUBSTITUTED ARYL IODIDE WITH OLEFIN IN ESTER SOLVENT | EASTMAN KODAK COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0388322-A1 | Preparation of 4-substituted aryl olefins | EASTMAN KODAK COMPANY (US) | 1990-09-19 | — | — | EP | disclosed |
| WO-1990009973-A1 | PREPARATION OF 4-SUBSTITUTED ARYL OLEFINS | EASTMAN KODAK COMPANY (US) | 1990-09-07 | — | — | WO | disclosed |
| US-4940657-A | Photographic spectral sensitizing dye | MITSUBISHI PAPER MILLS LIMITED (JP) | 1990-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240254138-A1 | TRICYCLIC PYRIMIDINES AS CYCLIN-DEPENDENT KINASE 7 (CDK7) INHIBITORS | CDK7, CDK2, CCNK | GPR35 2264/4885MAPK1 364/4885TP53 287/4885 |
| US-20250171427-A1 | THERAPEUTIC COMPOUNDS | IL17A, IL2, IL36G | GPR35 620/4885MAPK1 1728/4885TP53 779/4885 |
| US-20250154107-A1 | 3,4-Dihydroisoquinolin-1(2H)-Ones Derivatives as STING Antagonists and the Use Thereof | STING1, IRF3, MAVS | GPR35 827/4885MAPK1 3340/4885TP53 1003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.