Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | RXFP3 | Q9NSD7 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699521 | 0.79 | MAPT (0.61) | KMT2AMEN1RXFP3ALDH1A1LMNA | |
| SCHEMBL22340867 | 0.76 | CA1 (0.64) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL4701004 | 0.76 | KMT2A (0.74) | KMT2AMEN1LMNACYP1A2SMN1; SMN2 | |
| SCHEMBL4701009 | 0.76 | KMT2A (0.74) | KMT2AMEN1LMNACYP1A2SMN1; SMN2 | |
| SCHEMBL4628697 | 0.74 | SCN2A (0.84) | ALDH1A1LMNAHTTCYP1A2NPC1 | |
| SCHEMBL4697181 | 0.73 | RXFP3 (0.52) | RXFP3ALDH1A1LMNACYP1A2POLB | |
| SCHEMBL25771679 | 0.72 | MIF (0.81) | KMT2AMEN1ALDH1A1HTTCYP1A2 | |
| SCHEMBL24211799 | 0.71 | MAOA (0.71) | KMT2AMEN1ALDH1A1LMNAMAOA | |
| SCHEMBL17560740 | 0.71 | CYP1A2 (0.73) | KMT2AMEN1ALDH1A1LMNAMAOA | |
| SCHEMBL2335529 | 0.71 | MAOA (0.71) | KMT2AMEN1ALDH1A1LMNAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | claimed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |