Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | IKBKB | O14920 | 5/20 | 0.40 |
| ▸ | NOS2 | P35228 | 11/20 | 0.39 |
| ▸ | NOS1 | P29475 | 8/20 | 0.39 |
| ▸ | NOS3 | P29474 | 7/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701133 | 0.91 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3IKBKBNOS2 | |
| SCHEMBL4703961 | 0.91 | IKBKB (0.40) | SLC6A2SLC6A4SLC6A3IKBKBNOS2 | |
| SCHEMBL4705848 | 0.90 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3IKBKBNOS2 | |
| SCHEMBL4704338 | 0.90 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3IKBKBNOS2 | |
| SCHEMBL4700035 | 0.88 | IKBKB (0.40) | SLC6A2SLC6A4SLC6A3IKBKBNOS2 | |
| SCHEMBL4703405 | 0.88 | IKBKB (0.40) | SLC6A2SLC6A4SLC6A3IKBKBNOS2 | |
| SCHEMBL4702963 | 0.85 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3IKBKBNOS2 | |
| SCHEMBL4703002 | 0.84 | DHFR (0.43) | SLC6A2SLC6A4SLC6A3IKBKBNOS2 | |
| SCHEMBL4699896 | 0.83 | IKBKB (0.37) | SLC6A2SLC6A4SLC6A3IKBKBNOS2 | |
| SCHEMBL4705855 | 0.82 | IKBKB (0.42) | SLC6A2SLC6A4SLC6A3IKBKBNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001867-A2 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2008-12-17 | — | — | EP | disclosed |
| EP-1508560-B1 | Intermediates for the preparation of substituted Phenylketoenols | BAYER CROPSCIENCE AG (DE) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007110340-A2 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-10-04 | — | — | WO | disclosed |
| EP-1028963-B1 | NOVEL SUBSTITUTED PHENYL KETO ENOLS | BAYER CROPSCIENCE AG (DE) | 2005-06-15 | — | — | EP | disclosed |
| EP-1508560-A2 | Substituted Phenylketoenols | Bayer CropScience AG (DE) | 2005-02-23 | — | — | EP | disclosed |
| EP-1028963-A1 | NOVEL SUBSTITUTED PHENYL KETO ENOLS | BAYER AG (DE) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999024437-A1 | NOVEL SUBSTITUTED PHENYL KETO ENOLS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-05-20 | — | — | WO | disclosed |