Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.45 |
| ▸ | CTSK | P43235 | 16/20 | 0.45 |
| ▸ | CTSL | P07711 | 15/20 | 0.45 |
| ▸ | CTSB | P07858 | 14/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699859 | 0.92 | CTSK (0.51) | CTSSCTSKCTSLCTSB | |
| SCHEMBL4700791 | 0.89 | CTSS (0.45) | CTSSCTSKCTSLCTSB | |
| SCHEMBL4699481 | 0.85 | CTSS (0.51) | CTSSCTSKCTSLCTSB | |
| SCHEMBL4701698 | 0.81 | CTSS (0.66) | CTSSCTSKCTSLCTSB | |
| SCHEMBL4698804 | 0.80 | CTSL (0.66) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6236603 | 0.78 | CTSS (0.49) | CTSSCTSKCTSLCTSB | |
| SCHEMBL4699259 | 0.78 | CTSK (0.60) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6210052 | 0.77 | CTSK (0.57) | CTSSCTSKCTSLCTSB | |
| SCHEMBL4704586 | 0.74 | CTSS (0.44) | CTSSCTSKCTSLCTSB | |
| SCHEMBL4699860 | 0.74 | CTSK (0.72) | CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372655-B1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA LTD (CA) | 2008-10-01 | — | — | EP | claimed |