Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1250100 | 0.81 | AKR1B1 (0.38) | ALDH1A1PIM1MAPTHPGDCASP6 | |
| SCHEMBL9941730 | 0.74 | NOS1 (0.49) | ALDH1A1MAPTHPGDCASP6CYP3A4 | |
| SCHEMBL30811696 | 0.72 | CYP3A4 (0.40) | ALDH1A1MAPTHPGDCYP3A4LMNA | |
| SCHEMBL2215478 | 0.72 | TDO2 (0.46) | PIM1PIM3NOS1 | |
| SCHEMBL30856168 | 0.72 | CYP1A2 (0.47) | ALDH1A1PIM1MAPTHPGDCYP3A4 | |
| SCHEMBL22655651 | 0.66 | MAPT (0.39) | ALDH1A1MAPTCYP3A4CYP1A2TSHR | |
| SCHEMBL3370857 | 0.65 | MAPT (0.61) | ALDH1A1HIF1AMAPTHPGDCYP3A4 | |
| SCHEMBL2595091 | 0.65 | MAPT (0.50) | ALDH1A1HIF1AMAPTHPGDCYP3A4 | |
| SCHEMBL16681282 | 0.63 | MAPT (0.53) | ALDH1A1HIF1AMAPTHPGDCYP3A4 | |
| SCHEMBL31437655 | 0.62 | MAPT (0.38) | ALDH1A1PIM1MAPTHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032065-A1 | INDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF INFLUENZA VIRUS INFECTION | GLAXO GROUP LIMITED (GB) | 2012-03-15 | — | — | WO | disclosed |