Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | TTK | P33981 | 6/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL463124 | 0.79 | TTK (0.35) | TTKSYK | |
| SCHEMBL470186 | 0.78 | TYK2 (0.45) | CCNE1CDK2FLT3TTKTYK2 | |
| SCHEMBL457296 | 0.76 | TRPM5 (0.32) | TTKSYK | |
| SCHEMBL456788 | 0.75 | CCNE1 (0.35) | CCNE1CDK2FLT3TTKIRAK4 | |
| SCHEMBL15084636 | 0.73 | CCNE1 (0.57) | CCNE1CDK2FLT3TYK2SYK | |
| SCHEMBL5461682 | 0.72 | CDK2 (0.56) | CCNE1CDK2FLT3TTK | |
| SCHEMBL13213694 | 0.71 | CDK2 (0.60) | CCNE1CDK2FLT3IRAK4TYK2 | |
| SCHEMBL3021286 | 0.71 | CDK2 (0.60) | CCNE1CDK2FLT3IRAK4TYK2 | |
| SCHEMBL17425406 | 0.70 | IRAK4 (0.34) | CCNE1CDK2FLT3TTKIRAK4 | |
| SCHEMBL456487 | 0.70 | TTK (0.52) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |