Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 3/20 | 0.45 |
| ▸ | TTK | P33981 | 9/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.36 |
| ▸ | CDK2 | P24941 | 8/20 | 0.36 |
| ▸ | FLT3 | P36888 | 8/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458935 | 0.80 | TTK (0.41) | TTK | |
| SCHEMBL458281 | 0.79 | TYK2 (0.40) | TYK2TTKCCNE1CDK2FLT3 | |
| SCHEMBL470189 | 0.78 | CCNE1 (0.42) | TYK2TTKCCNE1CDK2FLT3 | |
| SCHEMBL456366 | 0.77 | ERN1 (0.34) | TTK | |
| SCHEMBL456244 | 0.77 | TTK (0.33) | TTK | |
| SCHEMBL455869 | 0.75 | TYK2 (0.41) | TYK2TTKCCNE1CDK2FLT3 | |
| SCHEMBL470188 | 0.74 | TTK (0.74) | TTK | |
| SCHEMBL17425401 | 0.72 | TYK2 (0.37) | TYK2TTK | |
| SCHEMBL455984 | 0.71 | — | — | |
| SCHEMBL458280 | 0.70 | TYK2 (0.43) | TYK2TTKCCNE1CDK2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |