Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 19/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 19/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21766368 | 0.93 | OPRL1 (0.54) | OPRL1OPRM1OPRK1 | |
| SCHEMBL21766632 | 0.91 | OPRL1 (0.56) | OPRL1OPRM1 | |
| SCHEMBL4702248 | 0.87 | OPRL1 (0.55) | OPRL1OPRM1OPRK1 | |
| SCHEMBL19148275 | 0.85 | OPRL1 (0.48) | OPRL1OPRM1OPRK1 | |
| SCHEMBL19145436 | 0.84 | OPRL1 (0.54) | OPRL1OPRM1OPRK1 | |
| SCHEMBL4849182 | 0.83 | OPRM1 (0.74) | OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL4852374 | 0.83 | OPRM1 (0.75) | OPRL1OPRM1 | |
| SCHEMBL23316782 | 0.81 | EPHX1 (0.50) | OPRL1OPRM1 | |
| SCHEMBL2780075 | 0.80 | ALDH1A1 (0.53) | OPRL1OPRM1OPRK1 | |
| SCHEMBL19146068 | 0.78 | OPRL1 (0.58) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183184-A1 | 3-(Carboxyethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | GRUENENTHAL GMBH (DE) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183184-A1 | 3-(Carboxyethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | OPRK1, OPRD1, PKD2 | OPRL1 4/4885OPRM1 7/4885OPRK1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.