Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.62 |
| ▸ | PGR | P06401 | 8/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4704793 | 0.93 | NR3C1 (0.68) | NR3C1PGR | |
| SCHEMBL4704996 | 0.86 | NR3C1 (0.71) | NR3C1PGR | |
| SCHEMBL4703050 | 0.85 | NR3C1 (0.61) | NR3C1PGR | |
| SCHEMBL4705781 | 0.84 | NR3C1 (0.68) | NR3C1PGR | |
| SCHEMBL4705889 | 0.84 | PGR (0.67) | NR3C1PGR | |
| SCHEMBL4702885 | 0.83 | NR3C1 (0.85) | NR3C1PGR | |
| SCHEMBL4702567 | 0.82 | NR3C1 (0.58) | NR3C1PGR | |
| SCHEMBL4706431 | 0.82 | NR3C1 (0.54) | NR3C1PGR | |
| SCHEMBL4706734 | 0.82 | NR3C1 (0.60) | NR3C1PGR | |
| SCHEMBL4706695 | 0.82 | NR3C1 (0.60) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532113-B1 | SUBSTITUTED HIHYDROQUINOLINES AS GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMA (US) | 2008-08-06 | — | — | EP | claimed |