Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 3/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SCN1A | P35498 | 1/20 | 0.54 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.54 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ACACB | O00763 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706125 | 0.84 | EBP (0.72) | EBPSIGMAR1CYP2D6CYP1A2LTA4H | |
| SCHEMBL3149568 | 0.83 | EBP (0.69) | EBPSIGMAR1MAOBCYP2D6HTT | |
| SCHEMBL1735178 | 0.81 | MCHR1 (0.52) | ESR1MCHR1 | |
| SCHEMBL4088440 | 0.81 | CYP1A2 (0.59) | EBPSIGMAR1MAOBCYP2D6CYP1A2 | |
| SCHEMBL8984333 | 0.80 | L3MBTL1 (0.56) | CYP1A2LTA4HCYP2C19LMNAKMT2A | |
| SCHEMBL8350895 | 0.80 | TP53 (0.56) | CYP2D6CYP1A2LTA4HCYP2C9CYP2C19 | |
| SCHEMBL250102 | 0.80 | EBP (0.69) | EBPSIGMAR1CYP2D6CYP1A2LTA4H | |
| SCHEMBL5810064 | 0.80 | EBP (0.68) | EBPSIGMAR1CYP2D6CYP1A2LTA4H | |
| SCHEMBL3859832 | 0.80 | MEN1 (0.64) | EBPSIGMAR1MAOBCYP1A2LMNA | |
| SCHEMBL4693255 | 0.79 | ESR1 (0.70) | EBPSIGMAR1MAOBCYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660474-B1 | SUBSTITUTED THIOPHENES AND USES THEREOF | ASTRAZENECA AB (SE) | 2008-10-29 | — | — | EP | disclosed |