Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 20/20 | 0.49 |
| ▸ | DRD2 | P14416 | 17/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 14/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4705240 | 0.91 | DRD3 (0.58) | DRD3DRD2KCNH2HRH1 | |
| SCHEMBL4702422 | 0.90 | DRD3 (0.47) | DRD3DRD2KCNH2 | |
| SCHEMBL4701966 | 0.90 | DRD3 (0.56) | DRD3DRD2KCNH2HRH1 | |
| SCHEMBL4704001 | 0.88 | DRD3 (0.55) | DRD3DRD2KCNH2HRH1 | |
| SCHEMBL4702317 | 0.86 | DRD3 (0.56) | DRD3DRD2KCNH2 | |
| SCHEMBL4701331 | 0.85 | DRD3 (0.56) | DRD3DRD2KCNH2HRH1 | |
| SCHEMBL4706365 | 0.84 | DRD3 (0.57) | DRD3DRD2KCNH2HRH1 | |
| SCHEMBL4387104 | 0.83 | DRD3 (0.59) | DRD3DRD2KCNH2HRH1 | |
| SCHEMBL4701336 | 0.83 | DRD3 (0.47) | DRD3DRD2KCNH2HRH1 | |
| SCHEMBL6192786 | 0.83 | ALDH1A1 (0.53) | DRD3DRD2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594861-B1 | TRIAZOLE COMPOUNDS AND THE THERAPEUTIC USE THEREOF | ABBOTT GMBH & CO KG (DE) | 2008-06-18 | — | — | EP | disclosed |
| EP-1594861-A1 | TRIAZOLE COMPOUNDS AND THE THERAPEUTIC USE THEREOF | Abbott GmbH & Co. KG (DE) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004069830-A1 | TRIAZOLE COMPOUNDS AND THE THERAPEUTIC USE THEREOF | ABBOTT GMBH & CO. KG (DE) | 2004-08-19 | — | — | WO | disclosed |