Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.43 |
| ▸ | MMP1 | P03956 | 4/20 | 0.41 |
| ▸ | MMP13 | P45452 | 4/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388068 | 1.00 | GPR119 (0.43) | GPR119MMP1MMP13MMP3MMP7 | |
| SCHEMBL461338 | 1.00 | GPR119 (0.43) | GPR119MMP1MMP13MMP3MMP7 | |
| SCHEMBL2603257 | 0.86 | GPR119 (0.44) | GPR119MMP1MMP13MMP3MMP7 | |
| SCHEMBL121105 | 0.84 | GPR119 (0.48) | GPR119MMP1MMP13MMP3MMP7 | |
| SCHEMBL19450683 | 0.83 | MMP1 (0.43) | GPR119MMP1MMP13MMP3MMP7 | |
| SCHEMBL19450535 | 0.83 | MMP1 (0.43) | GPR119MMP1MMP13MMP3MMP7 | |
| SCHEMBL19434335 | 0.83 | GAA (0.59) | GAA | |
| SCHEMBL287966 | 0.82 | GPR119 (0.44) | GPR119MMP1MMP13MMP3MMP7 | |
| SCHEMBL29588954 | 0.82 | GPR119 (0.44) | GPR119MMP1MMP13MMP3MMP7 | |
| SCHEMBL8262852 | 0.82 | ALDH1A1 (0.53) | GPR119FAAHGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |