Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.70 |
| ▸ | PGR | P06401 | 10/20 | 0.70 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4704402 | 0.83 | NR3C1 (1.00) | NR3C1PGR | |
| SCHEMBL4705725 | 0.82 | PGR (0.53) | NR3C1PGR | |
| SCHEMBL4705677 | 0.82 | NR3C1 (0.71) | NR3C1PGR | |
| SCHEMBL4703462 | 0.81 | PGR (0.67) | NR3C1PGRAR | |
| SCHEMBL4706194 | 0.81 | PGR (0.55) | NR3C1PGR | |
| SCHEMBL4704371 | 0.79 | NR3C1 (0.68) | NR3C1PGR | |
| SCHEMBL4702755 | 0.78 | PGR (0.53) | NR3C1PGR | |
| SCHEMBL4702637 | 0.77 | NR3C1 (0.55) | NR3C1PGR | |
| SCHEMBL4703420 | 0.77 | NR3C1 (0.62) | NR3C1PGRAR | |
| SCHEMBL4702857 | 0.77 | PGR (0.48) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532113-B1 | SUBSTITUTED HIHYDROQUINOLINES AS GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMA (US) | 2008-08-06 | — | — | EP | claimed |