Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149962 | 0.89 | GPR119 (0.38) | GPR119NTRK1KCNH2CYP3A4CYP2C19 | |
| SCHEMBL149963 | 0.89 | GPR119 (0.38) | GPR119NTRK1KCNH2CYP3A4CYP2C19 | |
| SCHEMBL149964 | 0.89 | GPR119 (0.38) | GPR119NTRK1KCNH2CYP3A4CYP2C19 | |
| SCHEMBL470743 | 0.88 | GPR119 (0.36) | GPR119NTRK1KCNH2CYP3A4CYP2C19 | |
| SCHEMBL12064975 | 0.88 | GPR119 (0.39) | GPR119NTRK1KCNH2CYP3A4CYP2C19 | |
| SCHEMBL470525 | 0.87 | GPR119 (0.36) | GPR119NTRK1KCNH2CYP3A4CYP2C19 | |
| SCHEMBL12064983 | 0.86 | GPR119 (0.36) | GPR119KCNH2CYP3A4CYP2C19NR1H2 | |
| SCHEMBL121467 | 0.85 | GPR119 (0.38) | GPR119NTRK1KCNH2 | |
| SCHEMBL149552 | 0.85 | GPR119 (0.38) | GPR119NTRK1KCNH2 | |
| SCHEMBL470534 | 0.85 | GPR119 (0.41) | GPR119NTRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |