SCHEMBL470490 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	GPR119	Q8TDV5	9/20	0.40

▸	GPR183	P32249	1/20	0.37

▸	NTRK1	P04629	3/20	0.35

▸	MCHR1	Q99705	1/20	0.35

▸	RBP4	P02753	3/20	0.35

▸	TTR	P02766	2/20	0.35

▸	KCNH2	Q12809	1/20	0.34

▸	RET	P07949	3/20	0.33

▸	ACACB	O00763	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL470516	0.87	GPR119 (0.41)	GPR119GPR183NTRK1KCNH2ACACB
SCHEMBL470534	0.86	GPR119 (0.41)	GPR119GPR183NTRK1RBP4TTR
SCHEMBL147043	0.81	GPR119 (0.37)	GPR119NTRK1KCNH2
SCHEMBL119927	0.81	GPR119 (0.37)	GPR119NTRK1KCNH2
SCHEMBL470479	0.81	GPR119 (0.36)	GPR119NTRK1KCNH2
SCHEMBL12064975	0.81	GPR119 (0.39)	GPR119GPR183NTRK1KCNH2
SCHEMBL12064792	0.80	GPR119 (0.45)	GPR119GPR183KCNH2ACACB
SCHEMBL147233	0.80	GPR119 (0.39)	GPR119GPR183NTRK1KCNH2ACACB
SCHEMBL149962	0.80	GPR119 (0.38)	GPR119GPR183NTRK1KCNH2RET
SCHEMBL149964	0.80	GPR119 (0.38)	GPR119GPR183NTRK1KCNH2RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2011147951-A1	CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS	PROSIDION LIMITED (GB)	2011-12-01	—	—	WO	disclosed