Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470787 | 0.77 | GPR119 (0.32) | GPR119GPR183KCNH2 | |
| SCHEMBL470537 | 0.77 | GPR119 (0.39) | OPRK1GPR119 | |
| SCHEMBL120997 | 0.77 | GPR119 (0.34) | OPRK1GPR119GPR183KCNH2 | |
| SCHEMBL146465 | 0.77 | GPR119 (0.34) | OPRK1GPR119GPR183KCNH2 | |
| SCHEMBL470585 | 0.75 | GPR119 (0.35) | GPR119GPR183KCNH2 | |
| SCHEMBL461635 | 0.74 | GPR119 (0.44) | OPRK1GPR119GPR183 | |
| SCHEMBL470686 | 0.72 | GPR119 (0.40) | GPR119GPR183KCNH2 | |
| SCHEMBL470680 | 0.71 | ALOX5AP (0.39) | GPR119GPR183KCNH2 | |
| SCHEMBL461248 | 0.71 | GPR119 (0.45) | GPR119GPR183KCNH2 | |
| SCHEMBL461247 | 0.71 | GPR119 (0.45) | GPR119GPR183KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |