Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1775324 | 0.81 | GRM5 (0.36) | GRM5MAPK1KDM4EL3MBTL1LMNA | |
| SCHEMBL2244245 | 0.78 | DCPS (0.34) | GRM5KDM4EL3MBTL1 | |
| SCHEMBL1775264 | 0.73 | POLB (0.36) | MAPK1KDM4ELMNA | |
| SCHEMBL4707666 | 0.72 | GRM5 (0.40) | GRM5MAPK1KDM4EL3MBTL1LMNA | |
| SCHEMBL1774617 | 0.69 | GRM5 (0.30) | GRM5KDM4EL3MBTL1 | |
| SCHEMBL1776124 | 0.69 | GRM5 (0.36) | GRM5KDM4EL3MBTL1LMNA | |
| SCHEMBL10123166 | 0.63 | POLB (0.37) | KDM4EL3MBTL1LMNA | |
| SCHEMBL4707031 | 0.60 | LMNA (0.38) | GRM5MAPK1KDM4ELMNA | |
| SCHEMBL11723136 | 0.58 | POLB (0.57) | MAPK1LMNA | |
| SCHEMBL15823276 | 0.56 | CSNK1D (0.42) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831226-A4 | CHIRAL FUSED 1,2 IMIDAZO 4,5-c RING COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2008-11-05 | — | — | EP | disclosed |
| EP-1831226-A2 | CHIRAL FUSED 1,2 IMIDAZO 4,5-c RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006074003-A2 | CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-07-13 | — | — | WO | disclosed |