Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 10/20 | 0.41 |
| ▸ | RORC | P51449 | 5/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4708122 | 0.95 | RORB (0.39) | RORBRORCIDH1GRM2VNN1 | |
| SCHEMBL4705879 | 0.94 | RORB (0.42) | RORBRORCIDH1GRM2HTT | |
| SCHEMBL4706229 | 0.93 | IDH1 (0.44) | RORBRORCIDH1GRM2GPBAR1 | |
| Tradipitant SCHEMBL2898629 | 0.92 | RORB (0.42) | RORBRORCIDH1GRM2TACR1 | |
| Tradipitant SCHEMBL29810017 | 0.92 | RORB (0.42) | RORBRORCIDH1GRM2TACR1 | |
| SCHEMBL4707172 | 0.91 | RORB (0.46) | RORBRORCGRM2 | |
| SCHEMBL4707133 | 0.91 | RORB (0.40) | RORBRORCIDH1GRM2GPBAR1 | |
| SCHEMBL4706981 | 0.89 | IDH1 (0.42) | RORBRORCIDH1VNN1 | |
| SCHEMBL4708632 | 0.88 | RORB (0.42) | RORBRORCIDH1GRM2TACR1 | |
| SCHEMBL4708296 | 0.88 | RORB (0.41) | RORBRORCIDH1GRM2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |