Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 8/20 | 0.42 |
| ▸ | RORC | P51449 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27538912 | 0.94 | RORB (0.44) | RORBRORCHTTL3MBTL1POLB | |
| SCHEMBL4705482 | 0.94 | RORB (0.41) | RORBRORCHTTL3MBTL1IDH1 | |
| SCHEMBL4707594 | 0.92 | RORB (0.43) | RORBRORCHTTL3MBTL1POLB | |
| SCHEMBL4708122 | 0.91 | RORB (0.39) | RORBRORCIDH1GRM2 | |
| SCHEMBL4704941 | 0.88 | RORB (0.40) | RORBRORCTP53 | |
| SCHEMBL4708283 | 0.87 | RORB (0.39) | RORBRORCIDH1GRM2 | |
| SCHEMBL4707066 | 0.87 | RORB (0.41) | RORBRORCIDH1GRM2 | |
| SCHEMBL4708468 | 0.87 | RORB (0.41) | RORBRORCIDH1GRM2 | |
| SCHEMBL4706229 | 0.87 | IDH1 (0.44) | RORBRORCIDH1GRM2SMN1; SMN2 | |
| Tradipitant SCHEMBL29810017 | 0.85 | RORB (0.42) | RORBRORCIDH1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |