Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | RET | P07949 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457627 | 0.88 | DPP4 (0.34) | DPP4DPP7DPP8DPP9NR1H2 | |
| SCHEMBL458009 | 0.86 | DPP4 (0.35) | DPP4DPP7DPP8DPP9NR1H2 | |
| SCHEMBL12064985 | 0.83 | DPP4 (0.33) | DPP4DPP7DPP8DPP9NR1H2 | |
| SCHEMBL470798 | 0.80 | DPP4 (0.32) | DPP4DPP7DPP8DPP9NR1H2 | |
| SCHEMBL152374 | 0.80 | GPR119 (0.39) | DPP4GPR119 | |
| SCHEMBL470805 | 0.80 | DPP4 (0.32) | DPP4DPP7DPP8DPP9NR1H2 | |
| SCHEMBL12064592 | 0.79 | NR1H2 (0.31) | DPP4DPP7DPP8DPP9NR1H2 | |
| SCHEMBL460032 | 0.79 | NTRK1 (0.38) | RET | |
| SCHEMBL470601 | 0.79 | NTRK1 (0.38) | NR1H2GRM4RET | |
| SCHEMBL12064782 | 0.78 | PDE4B (0.42) | DPP4DPP8DPP9NR1H2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |