Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 13/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4705889 | 0.92 | PGR (0.67) | PGRNR3C1 | |
| SCHEMBL4704987 | 0.90 | PGR (0.57) | PGRNR3C1LMNAMAPT | |
| SCHEMBL4702754 | 0.84 | PGR (0.52) | PGRNR3C1 | |
| SCHEMBL4704793 | 0.83 | NR3C1 (0.68) | PGRNR3C1 | |
| SCHEMBL4702720 | 0.83 | NR3C1 (0.67) | PGRNR3C1 | |
| SCHEMBL4704371 | 0.81 | NR3C1 (0.68) | PGRNR3C1 | |
| SCHEMBL4705756 | 0.81 | PGR (0.86) | PGRNR3C1 | |
| SCHEMBL4703050 | 0.81 | NR3C1 (0.61) | PGRNR3C1 | |
| SCHEMBL4702889 | 0.80 | NR3C1 (0.68) | PGRNR3C1 | |
| SCHEMBL4702496 | 0.80 | NR3C1 (0.70) | PGRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532113-B1 | SUBSTITUTED HIHYDROQUINOLINES AS GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMA (US) | 2008-08-06 | — | — | EP | claimed |