SCHEMBL470596

SCHEMBL470596

C[C@@H](OS(C)(=O)=O)C1CCNCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.35
CYP3A4 P08684 1/20 0.35
GABRA1 P14867 1/20 0.35
TSHR P16473 1/20 0.35
GABRG2 P18507 1/20 0.35
NFKB1 P19838 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
GABRA6 Q16445 1/20 0.35
SLC6A2 P23975 3/20 0.34
SLC6A4 P31645 3/20 0.34
SLC6A3 Q01959 3/20 0.34
CPN1 P15169 1/20 0.32
CPB2 Q96IY4 1/20 0.32
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14777975 0.84 ALDH1A1 (0.57) ALDH1A1TSHR
SCHEMBL14297001 0.80 ALDH1A1 (0.52) ALDH1A1
SCHEMBL14779338 0.80 ALDH1A1 (0.52) ALDH1A1
SCHEMBL9673176 0.80 ALDH1A1 (0.52) ALDH1A1
SCHEMBL1672558 0.78 ALDH1A1 (0.50) ALDH1A1MMP2
Tert-Butyl Formate SCHEMBL27887941 0.77 TDP1 (0.35) ALDH1A1
SCHEMBL4665794 0.77 ALDH1A1 (0.35) ALDH1A1LMNACYP3A4GABRA1TSHR
SCHEMBL1373078 0.75 ALDH1A1 (0.46) ALDH1A1
SCHEMBL30962982 0.75 ALDH1A1 (0.46) ALDH1A1
SCHEMBL458925 0.73 CPN1 (0.34) ALDH1A1LMNACYP3A4GABRA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151638-A2 COMPOUNDS FOR FGFRS INHIBITORS COGENT BIOSCIENCES, INC. (US) 2024-07-18 WO disclosed
WO-2011147951-A1 CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS PROSIDION LIMITED (GB) 2011-12-01 WO disclosed