Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470596 | 0.73 | ALDH1A1 (0.46) | CPN1CPB2ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL8552247 | 0.70 | OPRD1 (0.40) | ALDH1A1SLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL27512854 | 0.70 | CYP3A4 (0.42) | ALDH1A1SLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL10953420 | 0.67 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL2687432 | 0.66 | MMP2 (0.35) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL8781625 | 0.66 | ALDH1A1 (0.33) | ALDH1A1SLC6A4 | |
| SCHEMBL8647710 | 0.66 | CPN1 (0.30) | CPN1CPB2 | |
| SCHEMBL2686498 | 0.65 | MMP2 (0.38) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL4665794 | 0.65 | ALDH1A1 (0.35) | ALDH1A1SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL13186646 | 0.63 | KDM4E (0.36) | CPN1CPB2ALDH1A1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |