Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4708394 | 0.89 | RXFP1 (0.44) | RXFP1MAPTPOLBLMNATP53 | |
| SCHEMBL4705251 | 0.82 | MAPT (0.52) | MAPTPOLBLMNATP53KMT2A | |
| SCHEMBL5796761 | 0.79 | KCNH2 (0.44) | POLBSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL4705947 | 0.79 | MAPT (0.44) | MAPTPOLBTP53SMN1; SMN2KCNH2 | |
| SCHEMBL4707435 | 0.78 | TP53 (0.44) | MAPTPOLBLMNATP53KMT2A | |
| SCHEMBL4707117 | 0.78 | TACR1 (0.45) | MAPTPOLBLMNATP53KMT2A | |
| SCHEMBL4707175 | 0.77 | MAPT (0.46) | MAPTPOLBLMNATP53KMT2A | |
| SCHEMBL4705003 | 0.74 | ALDH1A1 (0.40) | POLBTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4706712 | 0.71 | TP53 (0.52) | MAPTPOLBLMNATP53KMT2A | |
| SCHEMBL6480543 | 0.70 | ALDH1A1 (0.36) | MAPTTP53SMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |