Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470585 | 0.86 | GPR119 (0.35) | GPR119GPR183ACACBALOX5AP | |
| SCHEMBL12064808 | 0.85 | ALOX5AP (0.35) | GPR119GPR183ALOX5AP | |
| SCHEMBL12064853 | 0.77 | ALDH1A1 (0.34) | GPR119GPR183 | |
| SCHEMBL462547 | 0.76 | GPR119 (0.32) | GPR119GPR183ACACBALOX5AP | |
| SCHEMBL462545 | 0.76 | GPR119 (0.32) | GPR119GPR183ACACBALOX5AP | |
| SCHEMBL462546 | 0.76 | GPR119 (0.32) | GPR119GPR183ACACBALOX5AP | |
| SCHEMBL470695 | 0.76 | DPP4 (0.39) | GPR119 | |
| SCHEMBL470902 | 0.75 | DPP4 (0.34) | GPR119GPR183ACACB | |
| SCHEMBL463070 | 0.75 | GPR119 (0.32) | GPR119GPR183 | |
| SCHEMBL463068 | 0.75 | GPR119 (0.32) | GPR119GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |