Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 6/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.32 |
| ▸ | FPR1 | P21462 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4706558 | 0.92 | OPRM1 (0.39) | CDK2OPRM1KDM4CFPR1FPR2 | |
| SCHEMBL4705791 | 0.86 | OPRM1 (0.39) | CDK2OPRM1KDM4CFPR1FPR2 | |
| SCHEMBL4197712 | 0.84 | NAMPT (0.36) | NAMPTUTS2RCHEK1KDM4CPIM3 | |
| SCHEMBL4706509 | 0.84 | OPRM1 (0.36) | OPRM1FPR1FPR2 | |
| Cyclohexane SCHEMBL4194020 | 0.81 | KDM4C (0.38) | NAMPTOPRM1KDM4CFPR1FPR2 | |
| SCHEMBL4186546 | 0.78 | REN (0.36) | OPRM1KDM4CFPR1FPR2HDAC2 | |
| SCHEMBL4708835 | 0.78 | OPRM1 (0.40) | OPRM1KDM4CPIM3PIM2HDAC2 | |
| SCHEMBL4706830 | 0.78 | OPRM1 (0.40) | OPRM1FPR1FPR2 | |
| SCHEMBL4707023 | 0.77 | OPRM1 (0.39) | OPRM1FPR1FPR2 | |
| SCHEMBL4708771 | 0.76 | KDM4C (0.40) | CDK2OPRM1KDM4CHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |