Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | F9 | P00740 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4705791 | 0.86 | OPRM1 (0.39) | OPRM1S1PR4S1PR5EPHX1FPR1 | |
| SCHEMBL4706558 | 0.85 | OPRM1 (0.39) | OPRM1S1PR4S1PR5EPHX1FPR1 | |
| SCHEMBL4706330 | 0.84 | AKT1 (0.36) | OPRM1FPR1FPR2 | |
| SCHEMBL4706830 | 0.83 | OPRM1 (0.40) | OPRM1S1PR4S1PR5EPHX1FPR1 | |
| SCHEMBL4706438 | 0.83 | F10 (0.40) | OPRM1S1PR4S1PR5F9F10 | |
| SCHEMBL4707023 | 0.83 | OPRM1 (0.39) | OPRM1S1PR4S1PR5FPR1FPR2 | |
| Cyclopropane SCHEMBL4190988 | 0.82 | EPHX1 (0.37) | OPRM1EPHX1HCAR1TAS1R3TAS1R1 | |
| SCHEMBL4190982 | 0.81 | HTR1A (0.36) | OPRM1EPHX1FPR1FPR2HCAR1 | |
| SCHEMBL4707718 | 0.77 | OPRM1 (0.40) | OPRM1S1PR4S1PR5 | |
| SCHEMBL4708771 | 0.73 | KDM4C (0.40) | OPRM1S1PR4S1PR5F9F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |