Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470849 | 0.88 | GPR119 (0.41) | GPR119OGAACACBAOC3 | |
| SCHEMBL19449870 | 0.80 | GPR119 (0.44) | GPR119OGA | |
| SCHEMBL19450640 | 0.80 | GPR119 (0.44) | GPR119OGA | |
| SCHEMBL459455 | 0.79 | GPR119 (0.33) | GPR119ACACB | |
| SCHEMBL19450729 | 0.78 | OGA (0.47) | GPR119OGA | |
| SCHEMBL470833 | 0.76 | OGA (0.45) | GPR119OGA | |
| SCHEMBL19434401 | 0.76 | OGA (0.45) | GPR119OGA | |
| SCHEMBL19457226 | 0.76 | GPR119 (0.50) | GPR119OGA | |
| SCHEMBL19434276 | 0.76 | OGA (0.45) | GPR119OGA | |
| SCHEMBL21643095 | 0.75 | OGA (0.36) | GPR119OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |