Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 3/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459456 | 0.80 | GPR119 (0.41) | GPR119SMOACACB | |
| SCHEMBL470645 | 0.79 | GPR119 (0.40) | GPR119ACACB | |
| SCHEMBL12989025 | 0.79 | ACHE (0.38) | GPR119HRH3HRH4 | |
| SCHEMBL470849 | 0.77 | GPR119 (0.41) | GPR119ACACB | |
| SCHEMBL470548 | 0.76 | HRH3 (0.38) | GPR119HRH3HRH4 | |
| SCHEMBL9925927 | 0.75 | MAPT (0.47) | GPR119HRH4 | |
| SCHEMBL470678 | 0.75 | GPR119 (0.41) | GPR119HRH3 | |
| SCHEMBL8513708 | 0.71 | SMO (0.42) | GPR119SMOHRH4 | |
| SCHEMBL11919298 | 0.71 | CKS1B (0.49) | GPR119HRH3HRH4 | |
| SCHEMBL470748 | 0.70 | GPR119 (0.47) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |