Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | ACACB | O00763 | 5/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470645 | 0.88 | GPR119 (0.40) | GPR119ACACBOGAAOC3 | |
| SCHEMBL19450534 | 0.81 | GPR119 (0.45) | GPR119KCNH2ACACBOGAHCRTR1 | |
| SCHEMBL19450805 | 0.81 | GPR119 (0.45) | GPR119KCNH2ACACBOGAHCRTR1 | |
| SCHEMBL148369 | 0.81 | SIGMAR1 (0.39) | GPR119KCNH2ACACBHCRTR1HCRTR2 | |
| SCHEMBL121128 | 0.81 | SIGMAR1 (0.39) | GPR119KCNH2ACACBHCRTR1HCRTR2 | |
| SCHEMBL1721058 | 0.80 | CHRM2 (0.39) | GPR119KCNH2ACACB | |
| SCHEMBL19450757 | 0.79 | GPR119 (0.48) | GPR119KCNH2ACACBOGAHCRTR1 | |
| SCHEMBL459455 | 0.77 | GPR119 (0.33) | GPR119ACACB | |
| SCHEMBL470546 | 0.77 | GPR119 (0.49) | GPR119KCNH2ACACBOGAHCRTR1 | |
| SCHEMBL22514061 | 0.77 | GPR119 (0.46) | GPR119KCNH2ACACBOGAHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |