Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6125565 | 0.87 | DPP4 (0.63) | DPP4MEN1KMT2ACCR5DRD2 | |
| SCHEMBL14730218 | 0.87 | DPP4 (0.63) | DPP4MEN1KMT2ACCR5DRD2 | |
| SCHEMBL14722977 | 0.86 | DPP4 (0.58) | DPP4CCR5DRD2DRD3ACHE | |
| SCHEMBL12064538 | 0.86 | DPP4 (0.58) | DPP4CCR5DRD2DRD3ACHE | |
| SCHEMBL14722978 | 0.86 | DPP4 (0.58) | DPP4CCR5DRD2DRD3ACHE | |
| SCHEMBL149732 | 0.84 | DPP4 (0.64) | DPP4CCR5DRD2DRD3 | |
| SCHEMBL461966 | 0.84 | DPP4 (0.64) | DPP4CCR5DRD2DRD3 | |
| SCHEMBL149731 | 0.84 | DPP4 (0.64) | DPP4CCR5DRD2DRD3 | |
| SCHEMBL149730 | 0.84 | DPP4 (0.64) | DPP4CCR5DRD2DRD3 | |
| SCHEMBL14723602 | 0.84 | DPP4 (0.61) | DPP4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |