Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | CAMK1D | Q8IU85 | 2/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RIPK4 | P57078 | 1/20 | 0.34 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.34 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.34 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.34 |
| ▸ | PNCK | Q6P2M8 | 1/20 | 0.34 |
| ▸ | CAMK1G | Q96NX5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470547 | 0.87 | GPR119 (0.45) | GPR119GPR183KCNH2HRH4HRH3 | |
| SCHEMBL470585 | 0.87 | GPR119 (0.35) | GPR119GPR183KCNH2HRH4HRH3 | |
| SCHEMBL13186518 | 0.87 | GPR119 (0.44) | GPR119GPR183KCNH2HRH4HRH3 | |
| SCHEMBL470632 | 0.85 | GPR119 (0.58) | GPR119GPR183KCNH2ACACB | |
| SCHEMBL12064841 | 0.81 | GPR119 (0.41) | GPR119GPR183KCNH2CYP2C19 | |
| SCHEMBL470644 | 0.80 | GPR119 (0.40) | GPR119GPR183KCNH2CYP2C19 | |
| SCHEMBL470522 | 0.78 | GPR119 (0.50) | GPR119GPR183KCNH2 | |
| SCHEMBL470907 | 0.78 | GPR119 (0.40) | GPR119GPR183KCNH2CYP2C19 | |
| Hydrochloric Acid SCHEMBL461931 | 0.77 | DPP4 (0.49) | GPR119GPR183KCNH2 | |
| SCHEMBL470659 | 0.77 | GPR119 (0.39) | GPR119GPR183KCNH2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |