Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 16/20 | 0.39 |
| ▸ | ACACA | Q13085 | 9/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470662 | 0.88 | GPR119 (0.33) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL470699 | 0.84 | DPP4 (0.35) | DPP4DPP8DPP9DPP7INPPL1 | |
| SCHEMBL470672 | 0.84 | ACACB (0.35) | ACACBACACA | |
| SCHEMBL470624 | 0.83 | GPR119 (0.33) | ACACBDPP4DPP8DPP9DPP7 | |
| SCHEMBL12064733 | 0.77 | MCHR1 (0.44) | ACACBACACADPP4DPP8DPP9 | |
| SCHEMBL12064798 | 0.77 | GPR119 (0.40) | DPP4 | |
| SCHEMBL12064977 | 0.77 | GPR119 (0.38) | — | |
| SCHEMBL462518 | 0.76 | DPP4 (0.43) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL470695 | 0.76 | DPP4 (0.39) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL12064555 | 0.76 | GPR119 (0.35) | DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |