Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470624 | 0.96 | GPR119 (0.33) | GPR119KCNH2GPR183POLBDPP4 | |
| SCHEMBL470695 | 0.89 | DPP4 (0.39) | GPR119KCNH2DPP4DPP8DPP9 | |
| SCHEMBL470676 | 0.88 | ACACB (0.39) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL470683 | 0.83 | OPRK1 (0.33) | GPR119GPR183 | |
| SCHEMBL470486 | 0.83 | NTRK1 (0.36) | GPR119 | |
| SCHEMBL470699 | 0.82 | DPP4 (0.35) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL470902 | 0.82 | DPP4 (0.34) | GPR119KCNH2GPR183DPP4DPP8 | |
| SCHEMBL12064798 | 0.82 | GPR119 (0.40) | GPR119KCNH2GPR183DPP4 | |
| SCHEMBL470671 | 0.82 | MCHR1 (0.37) | GPR119KCNH2GPR183DPP4DPP8 | |
| SCHEMBL470580 | 0.81 | NR1H2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |