Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 9/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470686 | 0.93 | GPR119 (0.40) | ALOX5APGPR119KCNH2GPR183EGFR | |
| SCHEMBL12064986 | 0.92 | ALOX5AP (0.40) | ALOX5APGPR119KCNH2GPR183CNR2 | |
| SCHEMBL12064808 | 0.81 | ALOX5AP (0.35) | ALOX5APGPR119KCNH2GPR183EGFR | |
| SCHEMBL470597 | 0.76 | GPR119 (0.45) | ALOX5APGPR119 | |
| SCHEMBL470651 | 0.75 | ALOX5AP (0.36) | ALOX5APGPR119KCNH2GPR183EGFR | |
| SCHEMBL462593 | 0.74 | ALOX5AP (0.33) | ALOX5APGPR119KCNH2EGFRKCNE1 | |
| SCHEMBL462592 | 0.74 | ALOX5AP (0.33) | ALOX5APGPR119KCNH2EGFRKCNE1 | |
| SCHEMBL462366 | 0.73 | ALOX5AP (0.37) | ALOX5APGPR119KCNH2GPR183CNR2 | |
| SCHEMBL6125564 | 0.73 | GPR119 (0.41) | ALOX5APGPR119 | |
| SCHEMBL19450516 | 0.72 | GPR119 (0.40) | ALOX5APGPR119KCNH2EGFRKCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |