SCHEMBL470686 — predicted protein targets

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	GPR119	Q8TDV5	13/20	0.40

▸	KCNH2	Q12809	4/20	0.40

▸	ALOX5AP	P20292	6/20	0.38

▸	EGFR	P00533	1/20	0.36

▸	KCNE1	P15382	1/20	0.36

▸	GPR183	P32249	1/20	0.33

▸	CCR1	P32246	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL470680	0.93	ALOX5AP (0.39)	GPR119KCNH2ALOX5APEGFRKCNE1
SCHEMBL12064986	0.90	ALOX5AP (0.40)	GPR119KCNH2ALOX5APGPR183
SCHEMBL19457227	0.79	GPR119 (0.42)	GPR119KCNH2ALOX5APEGFRKCNE1
SCHEMBL19450516	0.77	GPR119 (0.40)	GPR119KCNH2ALOX5APEGFRKCNE1
SCHEMBL28722271	0.76	GPR119 (0.33)	GPR119KCNH2ALOX5APEGFRKCNE1
SCHEMBL470682	0.75	GPR119 (0.46)	GPR119KCNH2ALOX5APEGFRKCNE1
SCHEMBL19434409	0.75	GPR119 (0.46)	GPR119KCNH2ALOX5APEGFRKCNE1
SCHEMBL28715691	0.75	GPR119 (0.43)	GPR119KCNH2EGFRKCNE1GPR183
SCHEMBL28715616	0.75	GPR119 (0.43)	GPR119KCNH2EGFRKCNE1GPR183
SCHEMBL28718765	0.75	GPR119 (0.43)	GPR119KCNH2EGFRKCNE1GPR183

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2011147951-A1	CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS	PROSIDION LIMITED (GB)	2011-12-01	—	—	WO	disclosed