Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 8/20 | 0.36 |
| ▸ | ACACB | O00763 | 5/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470918 | 0.82 | GPR119 (0.33) | ALOX5APGPR119KCNH2EGFRKCNE1 | |
| SCHEMBL470589 | 0.77 | DPP4 (0.42) | KCNH2 | |
| SCHEMBL470905 | 0.77 | GPR119 (0.33) | ALOX5APGPR119KCNH2EGFRKCNE1 | |
| SCHEMBL12064986 | 0.76 | ALOX5AP (0.40) | ALOX5APGPR119GPR183KCNH2 | |
| SCHEMBL470656 | 0.75 | ALOX5AP (0.34) | ALOX5APGPR119KCNH2EGFRKCNE1 | |
| SCHEMBL470680 | 0.75 | ALOX5AP (0.39) | ALOX5APGPR119GPR183KCNH2EGFR | |
| SCHEMBL470869 | 0.74 | GPR119 (0.44) | ACACBGPR119GPR183KCNH2 | |
| SCHEMBL470690 | 0.74 | ALOX5AP (0.32) | ALOX5AP | |
| SCHEMBL470686 | 0.73 | GPR119 (0.40) | ALOX5APGPR119GPR183KCNH2EGFR | |
| SCHEMBL470549 | 0.72 | ALOX5AP (0.30) | ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |