Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.32 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | C1S | P09871 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3791721 | 0.67 | ALOX5 (0.39) | ALDH1A1HPGDHDAC6 | |
| SCHEMBL3189574 | 0.65 | ALDH1A1 (0.34) | ALDH1A1HPGD | |
| SCHEMBL31047937 | 0.64 | ALDH1A1 (0.31) | ALDH1A1HPGD | |
| SCHEMBL4787649 | 0.62 | EPHX1 (0.50) | ALDH1A1HPGD | |
| Pivalate SCHEMBL14891014 | 0.62 | PDCD1 (0.48) | HIF1AALDH1A1HPGDBAZ2BBAZ2A | |
| SCHEMBL28816642 | 0.61 | — | — | |
| Carbamic Acid SCHEMBL31333088 | 0.60 | MAPT (0.42) | ALDH1A1HPGD | |
| SCHEMBL25094675 | 0.60 | PDCD1 (0.40) | HIF1AEPAS1HPGDBAZ2BBAZ2A | |
| SCHEMBL17632593 | 0.60 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL6632291 | 0.60 | CYP1A2 (0.54) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590337-B1 | ACYLAMINOTHIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME AS BETA-AMYLOID PEPTIDE PRODUCTION INHIBITORS | SANOFI AVENTIS (FR) | 2008-08-13 | — | — | EP | disclosed |