SCHEMBL4707240

SCHEMBL4707240

C=C(CCCCC)C(=O)OC#N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.40
CES2 O00748 4/20 0.40
CES1 P23141 4/20 0.40
ALDH1A1 P00352 3/20 0.40
AKR1B1 P15121 1/20 0.39
GPR84 Q9NQS5 7/20 0.38
PPARG P37231 6/20 0.38
PPARD Q03181 6/20 0.38
PPARA Q07869 6/20 0.38
HDAC11 Q96DB2 5/20 0.38
TLR2 O60603 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
FABP4 P15090 2/20 0.38
PTPN1 P18031 2/20 0.38
SLC22A6 Q4U2R8 1/20 0.38
SLC22A8 Q8TCC7 1/20 0.38
MEN1 O00255 1/20 0.38
ESR1 P03372 1/20 0.38
ALOX15 P16050 1/20 0.38
PDE4A P27815 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6021864 0.98 CES2 (0.42) TSHRCES2CES1ALDH1A1GPR84
SCHEMBL28412428 0.98 CES2 (0.42) TSHRCES2CES1ALDH1A1GPR84
SCHEMBL6249406 0.94 ALDH1A1 (0.41) TSHRCES2CES1ALDH1A1AKR1B1
SCHEMBL28024847 0.88 TSHR (0.42) TSHRALDH1A1GPR84PPARGPPARD
SCHEMBL28254932 0.86 ALDH1A1 (0.44) TSHRCES2CES1ALDH1A1
Water SCHEMBL7997185 0.79 CES2 (0.44) TSHRCES2CES1ALDH1A1AKR1B1
SCHEMBL898886 0.78
SCHEMBL9534599 0.78 CES2 (0.48) TSHRCES2CES1ALDH1A1AKR1B1
SCHEMBL27607745 0.76 ALDH1A1 (0.43) TSHRALDH1A1
SCHEMBL5006758 0.76 DGKA (0.52) TSHRCES2CES1ALDH1A1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11045997-B2 Water soluble support materials for high temperature additive manufacturing applications STRATASYS, INC. (US) 2021-06-29 US disclosed
US-20180370120-A1 WATER SOLUBLE SUPPORT MATERIALS FOR HIGH TEMPERATURE ADDITIVE MANUFACTURING APPLICATIONS STRATASYS, INC. 2018-12-27 US disclosed
WO-2017112687-A1 WATER SOLUBLE SUPPORT MATERIAL FOR HIGH TEMPERATURE ADDITIVE MANUFACTURING APPLICATIONS STRATASYS, INC. (US) 2017-06-29 WO disclosed
EP-1278101-B1 Silver salt photothermographic imaging material, and image recording method and image forming method by the use thereof KONICA MINOLTA MED & GRAPHIC (JP) 2008-07-02 EP disclosed
US-7384597-B2 Organic silver salt composition and manufacturing method thereof and photothermographic material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-06-10 US disclosed
US-7364841-B2 Comprising support having thereon light-insensitive organic silver salt grains, photosensitive silver halide grains, a reducing agent for silver ions and a binder; improved storage stability, image lasting quality; use in medical diagnosis and graphic arts KONICA MINOLTA & MEDICAL GRAPHIC, INC. (JP) 2008-04-29 US disclosed
US-7309565-B2 Process for treating photothermographic dry imaging material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-12-18 US disclosed
EP-1684115-B1 Photothermographic material KONICA MINOLTA MED & GRAPHIC (JP) 2007-08-08 EP disclosed
US-7229752-B2 Nonaqueous dispersion of particles insoluble in solvent; mixture containing metal complex as dopant KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-06-12 US disclosed
US-7220536-B2 Silver salt photothermographic dry imaging material, thermal development method of the same, and thermal development apparatus for the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-05-22 US disclosed
EP-1530079-A1 Silver salt photothermographic dry imaging material Konica Minolta Medical & Graphic, Inc. (JP) 2005-05-11 EP disclosed
US-20050089807-A1 Silver salt photothermographic dry imaging material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2005-04-28 US disclosed
EP-1519223-A1 Silver salt photothermographic dry imaging material Konica Minolta Medical & Graphic Inc. (JP) 2005-03-30 EP disclosed
US-20050064352-A1 Silver salt photothermographic dry imaging material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2005-03-24 US disclosed
US-6699649-B2 TO BE EFFECTIVELY EXPOSED EMPLOYING LASER IMAGERS AND LASER IMAGE SETTERS, AND CAN FORM CLEAR BLACK-AND-WHITE IMAGES EXHIBITING HIGH RESOLUTION KONICA CORPORATION (JP) 2004-03-02 US disclosed
US-20030203323-A1 Silver salt photothermographic dry imaging material and image recording method as well as image forming method using the same KONICA CORPORATION (JP) 2003-10-30 US disclosed
US-20030194658-A1 Silver salt photothermographic imaging material, and image recording method and image forming method by theuse thereof KONICA CORPORATION (JP) 2003-10-16 US disclosed
EP-1345075-A2 Silver salt photothermographic dry imaging material and image recording method as well as image forming method using the same KONICA CORPORATION (JP) 2003-09-17 EP disclosed
EP-1278101-A2 Silver salt photothermographic imaging material, and image recording method and image forming method by the use thereof KONICA CORPORATION (JP) 2003-01-22 EP disclosed
US-4021397-A LATEX, HYDROXYLAMINE SULFATE THE B. F. GOODRICH COMPANY (US) 1977-05-03 US disclosed