Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4708756 | 0.87 | KDM4E (0.41) | KDM4EPKMALDH1A1LMNAPOLB | |
| SCHEMBL4707788 | 0.87 | KDM4E (0.42) | KDM4EPKMALDH1A1LMNAPOLB | |
| SCHEMBL4708268 | 0.87 | KDM4E (0.38) | KDM4EPKMALDH1A1LMNAPOLB | |
| SCHEMBL4709526 | 0.86 | KDM4E (0.54) | KDM4EPKMALDH1A1SLC6A3LMNA | |
| SCHEMBL4197632 | 0.82 | KDM4E (0.39) | KDM4EPKMALDH1A1NTRK1LMNA | |
| SCHEMBL4707448 | 0.81 | KDM4E (0.47) | KDM4EPKMALDH1A1LMNAPOLB | |
| SCHEMBL4707002 | 0.81 | KDM4E (0.48) | KDM4EPKMALDH1A1LMNAPOLB | |
| SCHEMBL4708411 | 0.80 | GRM4 (0.40) | KDM4EPKMALDH1A1LMNAS1PR1 | |
| SCHEMBL4708104 | 0.78 | PKM (0.56) | KDM4EPKMALDH1A1LMNAPOLB | |
| SCHEMBL4709795 | 0.78 | KDM4E (0.49) | KDM4EPKMALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |