Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4709526 | 0.89 | KDM4E (0.54) | KDM4EPKMLMNAMAPTTP53 | |
| SCHEMBL4708411 | 0.83 | GRM4 (0.40) | KDM4EPKMLMNAMAPTTP53 | |
| SCHEMBL4707437 | 0.81 | KDM4E (0.41) | KDM4EPKMLMNAMAPTALDH1A1 | |
| SCHEMBL4708104 | 0.81 | PKM (0.56) | KDM4EPKMLMNAMAPTALDH1A1 | |
| SCHEMBL4189913 | 0.81 | KDM4E (0.45) | KDM4EPKMLMNAMAPTTP53 | |
| SCHEMBL4707002 | 0.81 | KDM4E (0.48) | KDM4EPKMLMNAMAPTTP53 | |
| SCHEMBL4707499 | 0.80 | PKM (0.48) | KDM4EPKMLMNAMAPTTP53 | |
| SCHEMBL4708306 | 0.79 | PKM (0.46) | KDM4EPKMLMNAMAPTTP53 | |
| SCHEMBL4708248 | 0.79 | KDM4E (0.52) | KDM4EPKMLMNAMAPTTP53 | |
| SCHEMBL4708790 | 0.78 | PKM (0.46) | KDM4EPKMLMNAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |