Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4709029 | 0.90 | KDM4E (0.49) | KDM4EPKMLMNAPOLBTP53 | |
| SCHEMBL4709795 | 0.87 | KDM4E (0.49) | KDM4EPKMLMNAPOLBTP53 | |
| SCHEMBL4707788 | 0.85 | KDM4E (0.42) | KDM4EPKMLMNAPOLBALDH1A1 | |
| SCHEMBL4706976 | 0.83 | PKM (0.46) | KDM4EPKMLMNAPOLBTP53 | |
| SCHEMBL4709526 | 0.83 | KDM4E (0.54) | KDM4EPKMLMNAPOLBTP53 | |
| SCHEMBL4708104 | 0.83 | PKM (0.56) | KDM4EPKMLMNAPOLBALDH1A1 | |
| SCHEMBL4707499 | 0.82 | PKM (0.48) | KDM4EPKMLMNAPOLBTP53 | |
| SCHEMBL4706576 | 0.81 | KDM4E (0.44) | KDM4EPKMLMNAPOLBTP53 | |
| SCHEMBL4707040 | 0.81 | KDM4E (0.44) | KDM4EPKMLMNAPOLBALDH1A1 | |
| SCHEMBL4707437 | 0.81 | KDM4E (0.41) | KDM4EPKMLMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |