Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4707456 | 1.00 | POLB (0.37) | POLBMEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL4705104 | 0.91 | POLB (0.35) | POLBMEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL4706878 | 0.88 | TSHR (0.37) | POLBMEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL4708475 | 0.87 | RORB (0.37) | KMT2ASMN1; SMN2GAAKDM4ERORC | |
| SCHEMBL4708474 | 0.87 | RORB (0.37) | KMT2ASMN1; SMN2GAAKDM4ERORC | |
| SCHEMBL4708201 | 0.83 | TSHR (0.35) | POLBMEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL4639395 | 0.80 | EPAS1 (0.40) | POLBMEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL4707988 | 0.78 | PTGER4 (0.36) | KMT2ASMN1; SMN2KDM4ERORCTACR1 | |
| SCHEMBL4707992 | 0.78 | PTGER4 (0.36) | KMT2ASMN1; SMN2KDM4ERORCTACR1 | |
| SCHEMBL4705694 | 0.77 | LMNA (0.43) | TSHRKMT2AGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |