Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4708027 | 0.85 | MEN1 (0.49) | ALDH1A1PKMGAAKDM4EMEN1 | |
| SCHEMBL4708279 | 0.84 | ALDH1A1 (0.43) | ALDH1A1PKMKDM4EKMT2A | |
| SCHEMBL4708553 | 0.84 | ALDH1A1 (0.48) | NPC1ALDH1A1PKMGAAMCOLN3 | |
| SCHEMBL4707205 | 0.83 | ALDH1A1 (0.49) | NPC1ALDH1A1PKMGAAMCOLN3 | |
| SCHEMBL4195126 | 0.83 | NPC1 (0.44) | NPC1ALDH1A1PKMGAAMCOLN3 | |
| SCHEMBL4707534 | 0.80 | PKM (0.44) | NPC1ALDH1A1PKMGAAMCOLN3 | |
| SCHEMBL4190323 | 0.80 | NPC1 (0.47) | NPC1ALDH1A1PKMGAAMCOLN3 | |
| SCHEMBL4190326 | 0.80 | NPC1 (0.47) | NPC1ALDH1A1PKMGAAMCOLN3 | |
| SCHEMBL4203662 | 0.79 | NPC1 (0.48) | NPC1ALDH1A1PKMGAAMCOLN3 | |
| Cyclohexanol SCHEMBL4190330 | 0.79 | NPC1 (0.50) | NPC1ALDH1A1PKMGAAMCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |