Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4707499 | 0.84 | PKM (0.48) | PKMKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL4707955 | 0.84 | PKM (0.53) | PKMKDM4ENPC1MEN1KMT2A | |
| SCHEMBL4189973 | 0.84 | PKM (0.42) | PKMKDM4ENPC1MEN1BRAF | |
| SCHEMBL4706182 | 0.81 | NPC1 (0.47) | PKMNPC1MEN1BRAFKMT2A | |
| SCHEMBL4707576 | 0.80 | NPC1 (0.45) | PKMKDM4ENPC1MEN1KMT2A | |
| SCHEMBL4708756 | 0.80 | KDM4E (0.41) | PKMKDM4ENPC1MEN1KMT2A | |
| SCHEMBL4708604 | 0.78 | ALDH1A1 (0.42) | PKMKDM4ENPC1ALDH1A1MCOLN3 | |
| SCHEMBL4707040 | 0.78 | KDM4E (0.44) | PKMKDM4EMEN1KMT2ACCR2 | |
| SCHEMBL4708104 | 0.78 | PKM (0.56) | PKMKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL4709526 | 0.76 | KDM4E (0.54) | PKMKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |