Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | SCN4A | P35499 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470519 | 0.90 | DPP4 (0.48) | DRD2DRD3DPP4FUCA1KDM1A | |
| SCHEMBL470568 | 0.86 | NPSR1 (0.42) | DRD2DRD3DPP4POLBALDH1A1 | |
| SCHEMBL13186638 | 0.83 | DRD2 (0.50) | DRD2DRD3DPP4POLBFUCA1 | |
| SCHEMBL13186825 | 0.83 | DRD2 (0.53) | DRD2DRD3DPP4FUCA1ALDH1A1 | |
| SCHEMBL12064538 | 0.83 | DPP4 (0.58) | DRD2DRD3DPP4FUCA1CCR5 | |
| SCHEMBL14722978 | 0.83 | DPP4 (0.58) | DRD2DRD3DPP4FUCA1CCR5 | |
| SCHEMBL14722977 | 0.83 | DPP4 (0.58) | DRD2DRD3DPP4FUCA1CCR5 | |
| SCHEMBL470646 | 0.83 | DRD2 (0.45) | DRD2DRD3DPP4FUCA1KDM1A | |
| SCHEMBL463520 | 0.82 | KMT2A (0.44) | DRD2DRD3DPP4SCN4APOLB | |
| SCHEMBL463519 | 0.82 | KMT2A (0.44) | DRD2DRD3DPP4SCN4APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |