Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470773 | 0.90 | DRD2 (0.41) | DPP4DRD2DRD3FUCA1KDM1A | |
| SCHEMBL13186825 | 0.88 | DRD2 (0.53) | DPP4DRD2DRD3FUCA1SIGMAR1 | |
| SCHEMBL13186638 | 0.88 | DRD2 (0.50) | DPP4DRD2DRD3FUCA1SIGMAR1 | |
| SCHEMBL470646 | 0.87 | DRD2 (0.45) | DPP4DRD2DRD3FUCA1SIGMAR1 | |
| SCHEMBL5924067 | 0.86 | DPP4 (0.48) | DPP4DRD2DRD3SIGMAR1GRIN2B | |
| SCHEMBL1724899 | 0.86 | DPP4 (0.48) | DPP4DRD2DRD3SIGMAR1GRIN2B | |
| SCHEMBL470568 | 0.85 | NPSR1 (0.42) | DPP4DRD2DRD3SIGMAR1CCR5 | |
| SCHEMBL149731 | 0.80 | DPP4 (0.64) | DPP4DRD2DRD3CCR5 | |
| SCHEMBL149730 | 0.80 | DPP4 (0.64) | DPP4DRD2DRD3CCR5 | |
| SCHEMBL461966 | 0.80 | DPP4 (0.64) | DPP4DRD2DRD3CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| WO-2010103334-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |